耿轶钊，男，汉族，1985年6月，博士，副教授。

【工作与教育经历】

2017.12-今 河北工业大学理学院，副教授

2014.09-2017.12 河北工业大学理学院，讲师

2011.09-2014.06 北京师范大学，核科学与技术学院，博士

2008.09-2011.01 河北工业大学，理学院，硕士

2004.09-2008.06 南开大学，物理科学学院，学士

【研究领域】

生物物理、统计物理

【主讲课程】

大学物理实验

【研究生招生学科方向】

硕士：生物学

【科研项目】

[1]河北省自然科学基金青年科学基金项目(No.2020202007), 驱动蛋白对微管结合位点的识别机制,2020-2022

[2]国家自然科学基金青年科学基金项目(No.11605038),驱动蛋白ADP释放机制研究,2017-2019

[3]国家自然科学基金应急管理项目(No.11545014),驱动蛋白ATP结合的应力调控机制,2016-2016

【代表性论文】

[1] Origin of the surprising mechanical stability of kinesin’s neck coiled coil, Journal of Chemical Theory and Computation, 2021, 17, 1017-1029.

[2] How kinesin-1 utilize the energy of nucleotide: The conformational changes and mechanochemical coupling in the unidirectional motion of kinesin-1, International Journal of Molecular Sciences, 2020, 21, 6977.

[3] Oscillation of S5 helix under different temperatures in determination of the open probability of TRPV1 channel, Chinese Physics B, 2020, 29, (9), 098701.

[4] Shaft function of kinesin-1’s α4 helix in the processive movement, Cellular and Molecular Bioengineering, 2019, 12, (4), 345-354.

[5] Protection-against-water-attack determined difference between strengths of backbone hydrogen bonds in kinesin’s neck zipper region, Chinese Physics B, 2018, 27, (2), 028704.

[6] Structural effects and competition mechanisms targeting the interactions between p53 and MDM2 for cancer therapy, Frontiers of Physics, 2017, 12, (3), 128908.

[7] Anchor effect of interactions between kinesin’s nucleotide-binding pocket and microtubule, Cellular and Molecular Bioengineering, 2017, 10, (2), 162-173.

[8] Initiation mechanism of kinesin’s neck linker docking process, Chinese Physics Letters, 2017, 34, (2), 028701.

[9] Covalent intermolecular interaction of the nitric oxide dimer (NO)2, Chinese Physics B, 2015, 24, (9), 093101.

[10] Locking function of a key residue in kinesin’s gating mechanism, Chinese Physics Letters, 2014, 31, (4), 048702.

[11] Initial conformation of kinesin’s neck linker, Chinese Physics B, 2014, 23, (10), 108701.

[12] Simulation study of interactions between kinesin’s neck linker and motor domain, Cellular and Molecular Bioengineering, 2014, 7, (1), 99-105.

[13] Mechanical amplification mechanism of kinesin’s β-domain, Archives of Biochemistry and Biophysics, 2014, 543, 10-14.

[14] An ab initio molecular dynamics study on hydrogen bonds between water molecules, The Journal of Chemical Physics, 2012, 136, 164313.

[15] Stochastic nature in cellular process, Communications in Theoretical Physics, 2011, 56, (5), 913-921.

[16] Radiation-induced robust oscillation and non-Gaussian fluctuation, Chinese Physics B, 2011, 20, (12), 128702.

【联系方式】

邮箱：gengyz@hebut.edu.cn